Chimpanzee faces under the magnifying glass: emerging methods reveal cross-species similarities and individuality

Independently, we created descriptive systems to characterize chimpanzee facial behavior, responding to a common need to have an objective, standardized coding system to ask questions about primate facial behaviors. Even with slightly different systems, we arrive at similar outcomes, with convergent conclusions about chimpanzee facial mobility. This convergence is a validation of the importance of the approach, and provides support for the future use of a facial action coding system for chimpanzees,ChimpFACS. Chimpanzees share many facial behaviors with those of humans. Therefore, processes and mechanisms that explain individual differences in facial activity can be compared with the use of a standardized systems such asChimpFACSandFACS. In this chapter we describe our independent methodological approaches, comparing how we arrived at our facial coding categories. We present some Action Descriptors (ADs) from Gaspar’s initial studies, especially focusing on an ethogram of chimpanzee and bonobo facial behavior, based on studies conducted between 1997 and 2004 at three chimpanzee colonies (The Detroit Zoo; Cleveland Metroparks Zoo; and Burger’s Zoo) and two bonobo colonies (The Columbus Zoo and Aquarium; The Milwaukee County Zoo). We discuss the potential significance of arising issues, the minor qualitative species differences that were found, and the larger quantitative differences in particular facial behaviors observed between species, e.g., bonobos expressed more movements containing particular action units (Brow Lowerer, Lip Raiser, Lip Corner Puller) compared with chimpanzees. The substantial interindividual variation in facial behavior within each species was most striking. Considering individual differences and the impact of development, we highlight the flexibility in facial activity of chimpanzees. We discuss the meaning of facial behaviors in nonhuman primates, addressing specifically individual attributes of Social Attraction, facial expressivity, and the connection of facial behavior to emotion. We do not rule out the communicative function of facial behavior, in which case an individual’s properties of facial behavior are seen as influencing his or her social life, but provide strong arguments in support of the role of facial behavior in the expression of internal states

Noise Assessment/Survey at ERAU Fleet Maintenance Hanger

One of the many hazards associated with aviation, and conducting aircraft maintenance, is the issuance of noise hazards. Federal agencies such as Occupational Health and Safety Administration have incorporated standards pertaining to threshold limit values and permissible exposure limits surrounding noise in the workplace. Our objective is to assist the work environment in the Embry-Riddle aviation hangar to assure personnel are protected from lasting effects of noise through this research. The method used for research in this paper was a combination of sound monitoring of the maintenance hangar using a sound level meter, noise dosimeter and the NIOSH Sound Level Meter application as well as using relevant previous research studies. The results of the sound monitoring determined that the noise level within the maintenance hangar was well below the OSHA Time Weighted Average of 85 dB, and the noise level peaked at 115.4 dB for a single impulse. It has been concluded that the maintenance hangar does not require a hearing conservation program at this time as the data indicates that noise levels are well within OSHA standards. However, the current data does not include the engine run-up operations

Elevation of Cicindela nigrior to species rank

Cicindela nigrior Schaupp (1884) has a complex taxonomic history as a subspecies, variety, and aberration of the morphologically plastic tiger beetle C. scutellaris. Schaupp gave the varietal name nigrior to what he apparently thought was a melanistic form of Cicindela scutellaris unicolor Dejean. Leng (1902) listed both nigrior and unicolor as varieties of scutellaris Say. However, Horn (1905) llsted nigrior and unicolor as aberrations of obscura Say (=scutellaris). Later he listed nigrior as a variety of scutellaris unicolor (Horn 1916). The Leng catalog (1920) shows both nigrior and unicolor as subspecies of scutellaris, while Vaurie (1950) and Boyd et al. (1982) placed nigrior as a synonym of unicolor. In this paper we raise the name "nigrior” to species level and present morphological, behavioral, and ecological data to Justify species status

Pattern recognition receptor MDA5 modulates CD8+ T cell- dependent clearance of west nile virus from the central nervous system

Many viruses induce type I interferon responses by activating cytoplasmic RNA sensors, including the RIG-I-like receptors (RLRs). Although two members of the RLR family, RIG-I and MDA5, have been implicated in host control of virus infection, the relative role of each RLR in restricting pathogenesis in vivo remains unclear. Recent studies have demonstrated that MAVS, the adaptor central to RLR signaling, is required to trigger innate immune defenses and program adaptive immune responses, which together restrict West Nile virus (WNV) infection in vivo. In this study, we examined the specific contribution of MDA5 in controlling WNV in animals. MDA5(−/−) mice exhibited enhanced susceptibility, as characterized by reduced survival and elevated viral burden in the central nervous system (CNS) at late times after infection, even though small effects on systemic type I interferon response or viral replication were observed in peripheral tissues. Intracranial inoculation studies and infection experiments with primary neurons ex vivo revealed that an absence of MDA5 did not impact viral infection in neurons directly. Rather, subtle defects were observed in CNS-specific CD8(+) T cells in MDA5(−/−) mice. Adoptive transfer into recipient MDA5(+/+) mice established that a non-cell-autonomous deficiency of MDA5 was associated with functional defects in CD8(+) T cells, which resulted in a failure to clear WNV efficiently from CNS tissues. Our studies suggest that MDA5 in the immune priming environment shapes optimal CD8(+) T cell activation and subsequent clearance of WNV from the CNS

CP and related phenomena in the context of Stellar Evolution

We review the interaction in intermediate and high mass stars between their evolution and magnetic and chemical properties. We describe the theory of Ap-star `fossil' fields, before touching on the expected secular diffusive processes which give rise to evolution of the field. We then present recent results from a spectropolarimetric survey of Herbig Ae/Be stars, showing that magnetic fields of the kind seen on the main-sequence already exist during the pre-main sequence phase, in agreement with fossil field theory, and that the origin of the slow rotation of Ap/Bp stars also lies early in the pre-main sequence evolution; we also present results confirming a lack of stars with fields below a few hundred gauss. We then seek which macroscopic motions compete with atomic diffusion in determining the surface abundances of AmFm stars. While turbulent transport and mass loss, in competition with atomic diffusion, are both able to explain observed surface abundances, the interior abundance distribution is different enough to potentially lead to a test using asterosismology. Finally we review progress on the turbulence-driving and mixing processes in stellar radiative zones.Comment: Proceedings of IAU GA in Rio, JD4 on Ap stars; 10 pages, 7 figure

A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse.

A randomized, multicentre, open-label, phase II study compared temozolomide (TMZ), an oral second-generation alkylating agent, and procarbazine (PCB) in 225 patients with glioblastoma multiforme at first relapse. Primary objectives were to determine progression-free survival (PFS) at 6 months and safety for TMZ and PCB in adult patients who failed conventional treatment. Secondary objectives were to assess overall survival and health-related quality of life (HRQL). TMZ was given orally at 200 mg/m(2)/day or 150 mg/m(2)/day (prior chemotherapy) for 5 days, repeated every 28 days. PCB was given orally at 150 mg/m(2)/day or 125 mg/m(2)/day (prior chemotherapy) for 28 days, repeated every 56 days. HRQL was assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30 [+3]) and the Brain Cancer Module 20 (BCM20). The 6-month PFS rate for patients who received TMZ was 21%, which met the protocol objective. The 6-month PFS rate for those who received PCB was 8% (P = 0.008, for the comparison). Overall PFS significantly improved with TMZ, with a median PFS of 12.4 weeks in the TMZ group and 8.32 weeks in the PCB group (P = 0.0063). The 6-month overall survival rate for TMZ patients was 60% vs. 44% for PCB patients (P = 0.019). Freedom from disease progression was associated with maintenance of HRQL, regardless of treatment received. TMZ had an acceptable safety profile; most adverse events were mild or moderate in severity

Prospectus, February 18, 1987

https://spark.parkland.edu/prospectus_1987/1005/thumbnail.jp

Dopant Spatial Distributions: Sample Independent Response Function And Maximum Entropy Reconstruction

We demonstrate the use of maximum entropy based deconvolution to reconstruct boron spatial distribution from the secondary ion mass spectrometry (SIMS) depth profiles on a system of variously spaced boron $\delta$-layers grown in silicon. Sample independent response functions are obtained using a new method which reduces the danger of incorporating real sample behaviour in the response. Although the original profiles of different primary ion energies appear quite differently, the reconstructed distributions agree well with each other. The depth resolution in the reconstructed data is increased significantly and segregation of boron at the near surface side of the $\delta$-layers is clearly shown.Comment: 5 two-columne pages, 3 postscript figures, to appear in Phys. Rev. B1

Prospectus, March 11, 1987

https://spark.parkland.edu/prospectus_1987/1008/thumbnail.jp